As a system, the mucus membrane or digestive tube is the first to appear by selforganisation in phylogenesis in the multicellular organisms and as hierarchy and chronology abides us, this is big.
This one, I repeat because it is in my opinion maybe "the most underrated part"some of us tend to forget in the story of the complexification of Life's organisms.
Often I get patient referrals from colleague osteopaths, which happen often to be ex-students from my old Alma Mater; usually they have "done some osteopathic techniques and tried out different 'hipster' stuff, they saw in the one or other postgrad, and then in frustrating amazement see the 'patients problem' reiterating over and over again, thus they refer them often to the old piping hippo...
Now I have not really kept stats about it, but my best educated guess is that in about 80 - 85 % of the cases, these patients have a fundamental "environmental" problem with their mucus membrane as a system (Endoderm), locally, regionally or systemically...and for most, there lies the key for their health returning, and the Boss NATURAL (individualized normal) to come home again. Now the mucus membrane is an extremely complex system where much is happening...
Nature demonstrates us that (repetitive) behavior creates Form in complex systems, in complex adaptive systems behavior builds up towards a state or moment of criticality and the the shift or internal reorganization or dimensional Form change happens... in other words the behavior is already usually recognizable for the diligent observers mind, before it really structures and takes form.
Hierarchy means that something has to be there before the next step, evolution or development can take place, under the motto you can't make an omelette without eggs.
Hierarchy thus says something about space, being present, filling a part of the space or not. Chronology says something about time, in time if you have eggs, then you need to break them to make an omelette... can't reverse that timeline hey?
Hierarchy and chronology of coming into FORM matters, because this story is also how the whole keeps behaving or functioning in other words.
Meaning the earlier a system appears, the more fundamental it is for that organisms normal functioning...and for those who have not read the rest of my stuff (you are wrong because they are really a summative story) go and read at least Annus Horribilis it is about Hierarchy and Chronology mostly: https://www.linkedin.com/pulse/annus-horribilis-max-girardin/
A FORM is normally adapted to its environment, or in some cases adapts the close environment to its needs (bee hives, termite hills, a birds nest, a human house etc), as long as these are all more or less in balance, the Form is "perfect" or in "harmony" in Still's words, meaning it behaves within the range of homeostasis, it can deal with the stimuli the environment throws at it, with absorption and metabolization of the stimuli as reaction, there is no disrupting pattern provoking brutal FORM change, all is in the green.
But when a or many stimuli disrupt these quiet normal waters...the Form has to notch up its reactions or responses and deal with the pattern(s) in its midst now....this means more or less always Form change, or internal reorganization...now 'in se' that is ok...but the consequence is that by the internal reorganization, to deal with these necessities to maintain itself, there will be an increase in order and thus per definition less potential...meaning that the overall resilience of the Form or at least a part of it, is diminished or in the end even practically lost